Nanoparticles introduced into the bloodstream encounter the immune complement system, a proteolytic cascade that bridges innate surveillance and adaptive responses. Complement activation can occur via ...

IIT Kanpur scientists have unlocked the mystery behind the C5aR2 immune receptor's unique function. Using advanced cryo-EM, ...

Our immune system works around the clock to protect us from bacteria, viruses, and other harmful germs. It also helps repair damaged tissues after injuries. One of its most important defense tools is ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

Rheumatoid arthritis is a chronic autoimmune disease that affects millions of people worldwide. This disease prompts the immune system to mistakenly attack body tissues, particularly joints, leading ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

SAN DIEGO -- There was a clinically meaningful reduction in proteinuria with iptacopan (Fabhalta), and a confirmed clinical benefit of alternative pathway inhibition, in a rare kidney disorder, ...

A conceptual illustration showing how ubiquitin-like 3 (UBL3) modification acts as a molecular “tag” that directs selected proteins into small extracellular vesicles (sEVs). Inside the secreting cell, ...

IIT Kanpur researchers, led by Professor Arun K Shukla, used cryo-EM to uncover the molecular basis of the atypical immune ...