Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a comprehensive software suite to create accurate models of DNA in biomolecular ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some ...

Seventy years ago, two male scientists, Francis Crick and James Watson, proclaimed they had discovered the secret of life: the structure of DNA. Since then, history has acknowledged how Rosalind ...

DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of their tertiary structures and binding mechanisms hinders their further ...