Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people. While it is well known for causing muscle weakness and stiffness, DM1 also ...

The same model also allows exploration of CICR in neurons, smooth muscle, and immune cells, expanding its clinical impact. With this insight, drug design can now focus on precision control of Ca²⁺ ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Can you explain what Myomaker Bio's lab-grown human muscle platform is and the challenge it aims to address in drug development? Myomaker Bio develops three-dimensional human-derived muscle organs and ...

The foreign body response is a clinically relevant process that can lead to issues with biocompatibility in implanted medical devices due to fibrosis. While the inflammatory nature of the foreign body ...