Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...

When Steve Carr, senior director of the Proteomics Platform at the Broad Institute of MIT and Harvard, began working in proteomics, the field was able to detect only the most abundant proteins in a ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...

Up to half of patients with Crohn's disease, an inflammatory bowel disease, develop a complication called fibrosis, where the gut becomes scarred and obstructed, causing pain and bloating. Currently, ...

In a recent study published in the journal Nature, researchers developed spatial aging clocks using single-cell transcriptomics to explore cell-type-specific interactions and their impact on brain ...

Chang leads assay and applications development at Takara Bio, driving the commercialization of novel spatial genomics products. She has extensive experience in single-cell multiomics technologies and ...

Recent advances in single-cell sequencing and spatial multi-omics have transformed our ability to resolve tumor ecosystems at unprecedented resolution.

MSK immunologist Dr. Andrea Schietinger and colleagues found that a 'triad' of immune cells is required to kill cancer cells. The discovery could alter the way doctors administer immunotherapies.

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...