For more than three decades, researchers studying genomes have relied on foundational resources such as Repbase and, more ...

Transposable elements (TEs) are discrete DNA sequences capable of moving within and between genomes, shaping genome architecture and function across all domains of life. They encompass two principal ...

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors ...

For years, researchers thought that most of DNA was passive "junk" and knew little about it. However, new findings are peeling back the odd and baffling world of transposons. Now, researchers have ...

Over a decade after sequencing the human genome, it has now become clear that the genome is not mostly ‘junk’ as previously thought. In fact, the ENCODE project consortium of dozens of labs and ...

To understand how organisms are related, researchers use molecular information to construct phylogenetic trees. Most of the time, scientists use thousands of protein-coding sequences to determine ...

Sankey diagram illustrating the inferred functions of TE-proximal genes. The width of connections between each vertical block represents the gene count, delineating GO term classifications associated ...

Researchers from Cleveland Clinic's Genome Center have outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer's disease in aging brains. In a report published in ...

Deep within tropical forests, sloths move at a pace that seems almost frozen in time. Their slow movements, low energy use, ...

Heterochromatin, sometimes known as the “dark side of the genome,” is a poorly studied fraction of DNA that makes up about half of our genetic material. For more than 50 years scientists have puzzled ...

Over a decade after sequencing the human genome, it has now become clear that the genome is not mostly 'junk' as previously thought. In fact, the ENCODE project consortium of dozens of labs and ...