MedCity News

The FDA’s Bayesian Guidance Could Quietly Reshape Clinical Trial Design

As clinical drug development becomes more complex and resource-intensive, the FDA’s recent draft guidance on the use of Bayesian statistical methods in clinical trials signals a move toward more ...

Where FIFA Rankings And World Cup Betting Markets Disagree

Compare FIFA rankings, betting odds, and prediction markets to see how each source estimates 2026 World Cup championship ...

Youngsters must learn fast, build often, and communicate better

Srikanth Velamakanni advises students and professionals to prioritize first principles thinking and continuous learning. He emphasizes building practical projects to solidify knowledge and retain ...
Nature

What is the expectation maximization algorithm?

Probabilistic models, such as hidden Markov models or Bayesian networks, are commonly used to model biological data. Much of their popularity can be attributed to the existence of efficient and robust ...
PsyPost on MSN

An international brain imaging analysis reveals how psychedelics rewire neural circuits

An international analysis combining brain imaging data from multiple independent studies has identified a common pattern in ...
IEEE

Bayesian Allocation Model: Marginal Likelihood-Based Model Selection for Count Tensors

Abstract: In this article, we introduce a dynamic generative model, the Bayesian allocation model (BAM), for modeling count data. BAM covers various probabilistic nonnegative tensor factorization (NTF ...
IEEE

Auxiliary Particle Implementation of Probability Hypothesis Density Filter

Abstract: Optimal Bayesian multi-target filtering is, in general, computationally impractical owing to the high dimensionality of the multi-target state. The probability hypothesis density (PHD) ...
bmjopensem.bmj

Bayesian approach to quantify morphological impact on performance in international elite freestyle swimming

Objectives The purpose of this study was to quantify the impact of morphological characteristics on freestyle swimming performance by event and gender. Design Height, mass, body mass index (BMI) and ...
Thorax

Comparative performance of endobronchial ultrasound-guided sampling techniques in patients with mediastinal lesions: a network meta-analysis

Background Comparative evidence on the diagnostic yield of endobronchial ultrasound (EBUS)-guided sampling techniques for ...
eLife

Frequency-dependent modulation of foveal contrast sensitivity by fine-scale exogenously triggered attention

Fine-scale exogenous attention within the foveola selectively enhances contrast gain at low-to-mid spatial frequencies while increasing response gain across a broad spatial frequency range.
BMJ Global Health

Ambient temperature variations and antimicrobial resistance: a multicountry analysis of non-linear relationships and temperature thresholds

Background Antimicrobial resistance (AMR) is an escalating global health crisis being worsened by climate change. Studies of ...
BMJ Open

Protocol for the economic evaluation of integrated longitudinal public health interventions in a cluster randomised controlled trial setting: the healthy life trajectories ...

Introduction In 2021, globally, cardiometabolic diseases (CMDs) accounted for 35% of the 1.73 billion disability-adjusted life years (DALYs) attributed to non-communicable diseases. The Healthy Life ...