As genome editing therapies move through clinical trials to regulatory approval, scientists continue the quest for the holy ...

The Argonautes represent a highly conserved gene family that is found in almost all eukaryotes and is even found in bacteria and archaea. Many members of the Argonaute gene family are found in the ...

The in vitro experiments that used the artificial genetic codes tested here did not provide support for the error minimization theory.

A new AAV-based gene therapy successfully improved seizures, behavior, and brain activity in fragile X syndrome mice, paving the way for clinical development.

Within the coding region, gRNAs annealing to the template strand were more effective than those against the nontemplate strand. The only exception was gRNA “cds_NT1,” which anneals to the nontemplate ...