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As the capabilities of large code models are gradually being unearthed, aiXcoder has consistently pondered on how to make these models more beneficial in real development scenarios. To this end, we ...

Large paralogous protein families are found throughout biology, the product of extensive gene duplication. To execute different functions inside cells, paralogs often acquire different specificities, ...

We identify the cell type–specific selection of T cells with a synonymous mitochondrial DNA variant in MT-CO1, reminiscent of the purifying selection of pathogenic alleles. Mechanistically, we ...

Since the “resolution revolution” (Kühlbrandt, 2014), single particle electron cryomicroscopy (cryo-EM) has established itself as a prime tool for determining the three dimensional structure of ...