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Objective Over half of patients with IBS have either diarrhoea (IBS-D) or a mixed stool pattern (IBS-M). The relative efficacy of licenced pharmacological therapies is unclear in the absence of ...

Correspondence to Professor Edoardo Savarino, Gastroenterology Unit, Department of Surgery, Oncology and Gastroenterology, University of Padua, Padova 35122, Italy; esavarino{at}libero.it Background ...

2 College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, China Objective To demonstrate an application of Bayesian model averaging (BMA) with generalised additive ...

Healthcare decisions should be based on all relevant evidence.1 Usually, this is provided by randomised controlled trials (RCTs) comparing two or more interventions for a condition affecting a target ...

3 Saudi Food and Drug Authority, Drug Sector, Riyadh, Saudi Arabia Design A systematic review and NMA of randomised clinical trials. Methods We conducted a systematic literature review to identify ...

Correspondence to: Dr Johan Thor Medical Management Centre, Berzelius väg 3, 5th floor, Karolinska Institutet, S-171 77 Stockholm, Sweden; johan.thor{at}ki.se Objective: To systematically review the ...