pggb builds pangenome variation graphs from a set of input sequences. A pangenome variation graph is a kind of generic multiple sequence alignment. It lets us understand any kind of sequence variation ...

This contribution is part of the special series of Inaugural Articles by members of the National Academy of Sciences elected in 2024. Many real-world networks change dynamically but can be notoriously ...

Objectives There is substantial disagreement about whether gluten-free foods should be prescribed on the National Health Service. We aim to describe time trends, variation and factors associated with ...

Global, regional, and country/territory-level data on key dimensions of human development, with interactive insights and publications. The human development data are globally comparable, linked to the ...

Proteinortho is a widely used tool to predict (co)-orthologous groups of genes for any set of species. It finds application in comparative and functional genomics, phylogenomics, and evolutionary ...

Molecular profiling technologies, such as RNA sequencing, offer new opportunities to better discover and understand the molecular networks involved in complex biological processes. Clinically ...

Introduction Use of home dialysis by centres in the UK varies considerably and is decreasing despite attempts to encourage greater use. Knowing what drives this unwarranted variation requires in-depth ...

There are three key aspects to genetic disease associations: comprehensive variant discovery, accurate allele-frequency determination, and an understanding of the pattern of normal variation and its ...

For small genomes, it is possible to study genetic variation by assembling whole genomes and then comparing them via whole-genome comparison 6,7. For large genomes, such as the human genome, complete ...