The brain encodes the statistical regularities of the environment in a task-specific yet flexible and generalizable format. Here, we seek to understand this process by bridging two parallel lines of ...

Vascular smooth muscle cells (VSMCs) phenotype switch from contractile to proliferative phenotype is a pathological hallmark in various cardiovascular diseases. Recently, a subset of long noncoding ...

Tumor-related hyperintensities in high b-value diffusion-weighted imaging (DWI) are radiologically important in the workup of gliomas. However, the white matter may also appear as hyperintense, which ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Single-target quantitative polymerase chain reaction (qPCR) is ...

G-protein-coupled-receptor (GPCR) signaling is exquisitely controlled to achieve spatial and temporal specificity. The endogenous protein kinase inhibitor peptide (PKI) confines the spatial and ...

Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, United States Engineering Research Center for Biorenewable Chemicals, Iowa State ...

Decreased hippocampal-prefrontal synchrony may mediate cognitive deficits in schizophrenia but it remains unclear which cells orchestrate this long-range synchrony. Parvalbumin- (PV) and ...

Autoimmune disease pathogenesis is driven by inflammation, induced partly by IgG autoantibody-containing immune complexes binding to Fc gamma receptors (FcγRs). These receptors are valid therapeutic ...

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T cells recognize virus-infected cells and tumor cells by detecting the presence of disease-specific peptide–major histocompatibility complexes (pMHC) with their clone-specific T-cell receptor. Both ...