A James Bond stunt show is mooted, alongside a Back to the Future “thrill ride”, and duffel-coated bear, Paddington, will headline a British Icon family zone. Universal United Kingdom Resort will open ...
Toolchains (Rustc, Cargo, libraries, etc.) Rustup (toolchain multiplexer) Crates.io (community-supplied Crates) with "sparse" index support. Incremental artifact downloading (with a configurable ...
Adenosine-to-Inosine (A-to-I) editing is an endogenous RNA modification in eukaryotes, catalyzed by adenosine deaminases acting on RNA (ADARs). This modification modulates the gene expression by ...
Human genes can generate multiple protein isoforms by alternative splicing (AS) of different sets of pre-mRNA exons, which enables another layer of regulatory control over gene function in development ...
Protein transport into the nucleus is mediated by transport receptors. Import of highly charged proteins, such as histone H1 and ribosomal proteins, requires a dimer of two transport receptors. In ...
A recently developed human norovirus cell culture system revealed that the presence of bile enhanced or was an essential requirement for the growth of certain genotypes. Before this discovery, ...
The high-resolution structures presented herein explain how ERp44, a multifunctional chaperone cycling in the early secretory pathway, exploits the endoplasmic reticulum (ER)–Golgi pH gradient to bind ...