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Objectives The aim of this study was to investigate acute opioid dose changes among patients started on a continuous subcutaneous infusion (CSCI) containing alfentanil or morphine within a specialist ...

Background Prescribed opioids are potent analgesics associated with high safety risks due to their adverse effects, drug-drug and drug-disease interactions and potential for dependency. To support the ...

Background In an evolving landscape of practices and policies, reviewing and incorporating the latest scientific evidence is necessary to ensure optimal clinical management for people with opioid use ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Article Views are the COUNTER-compliant sum of full text article downloads since ...

We describe the management by a pre-hospital medical team of a typical opioid toxidrome in a young man after consumption of an unknown substance with complete reversion after injection of unusually ...

Background The NHS has the target of reducing its carbon emission by 80% by 2032. Part of its strategy is using pharmaceuticals with a less harmful impact on the environment. Nitrous oxide is ...

Background For the treatment of breathlessness in heart failure (HF), most textbooks advocate the use of opioids. Yet, meta-analyses are lacking. Methods A systematic review was performed for ...

1 Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia 2 Pain Management Research Institute, Kolling Institute, University of Sydney, Sydney, NSW, ...

1 Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA 2 ...

Hepatobiliary scintigraphy is a diagnostic imaging study that uses a radioactive tracer to evaluate hepatocellular function and the biliary system. The production and flow of bile is tracked from the ...