A research team led by the Universitat Autònoma de Barcelona (UAB) has revealed how the genome is reorganized in 3D during male germ cell formation in vertebrates, leading to important new insights ...

Plant immunity research has undergone a transformative shift with the advent of spatial and single-cell technologies, ...

Discover why animal models fall short in AI drug discovery and how human-first datasets and functional genomics are changing ...

Among the assorted communities of brain cells contained within an 8 millimeter punch of cortex, scientists have captured what might reflect two pivotal microglial moments along the decades-long ...

Researchers from VIB, KU Leuven, the UK-DRI and Muna Therapeutics have uncovered a critical biological transition that may determine whether Alzheimer's disease pathology leads to dementia. Studying ...

A detailed description of the pipeline, methods, and results can be found in the following article: Giraud-Sauveur, F., Blampey, Q., Benkirane, H. et al. STHELAR, a multi-tissue dataset linking ...

Abstract: Spatially Resolved Transcriptomics (SRT) has revolutionized our understanding of gene expression within tissue microenvironments, yet accurately deciphering spatiotemporal ...

A core challenge in biology is understanding how processes in the body, such as cellular development and regeneration, unfold over long stretches of time, making them notoriously difficult to view at ...

In an unexpected finding, a new study flips on its head researchers' understanding of how precancerous pancreas lesions evolve into pancreatic cancer. The paradigm-changing discovery has tremendous ...

When an optometrist shines a bright light into your eyes, a vast, branching tree sprouts in your field of vision. This is the shadow of blood vessels. Though we normally can’t perceive them, these ...

Scientists have uncovered a hidden reason why cancer treatments don’t work equally well for everyone. Certain drugs can become trapped inside lysosomes within tumor cells, forming slow-release ...

The global initiative aims to profile up to 100,000 patient specimens to scale M-Optimus, the world model of biology, representing a ~20x increase in scale over existing data available in the world ...