Frontiers

Wheat aroma biomarkers induced by saline-alkali soil: based on HS-SPME-GC-MS and molecular docking

Retention Index (Exp) indicates experimental linear retention index; Retention Index (Lit) indicates retention index reported for reported in the literature. “-” indicates that no appropriate ...
eLife

Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants

This manuscript presents valuable findings showing that rapamycin directly activates the cool-sensing ion channel, TRPM8, acting through a different binding site than other small-molecule cooling ...
GitHub

Machine Learning and Molecular Docking Prediction of Potential Inhibitors against Dengue Virus.

This project aims at building an in silico pipeline to identify novel Dengue Virus inhibitors. We will incorporate Machine Learning (ML) and Molecular Modeling techniques into the pipeline. The ...
PNAS

Three mutations repurpose a plant karrikin receptor to a strigolactone receptor

Parasitic plants like witchweed cause huge losses in crop yield in Africa. A key part to the success of witchweed is to start its life cycle upon sensing small molecules called strigolactones, which ...
Frontiers

A Proline-Rich Element in the Type III Secretion Protein FlhB Contributes to Flagellar Biogenesis in the Beta- and Gamma-Proteobacteria

Flagella are bacterial organelles of locomotion. Their biogenesis is highly coordinated in time and space and relies on a specialized flagellar type III secretion system (fT3SS) required for the ...
PNAS

Structural basis for reversible photoswitching in Dronpa

Dronpa is a novel GFP-like fluorescent protein with exceptional light-controlled switching properties. It may be reversibly switched between a fluorescent on-state and a nonfluorescent off-state by ...